How Does Adipex Diet Pill Work?

Adipex is listed as an appetite suppressant and belongs to a class of drugs known as sympathomimetic amines. How Adipex works is not fully understood. It has been suggested that it might decrease your appetite, increase the amount of energy used by the body or by interacting with certain parts of the brain. Chances are Adipex is doing all of these things plus more but only further study will elucidate the full mechanism otherwise the mechanism has been speculated.



Adipex users have reported running into Adipex/Phentermine tolerance. In other words, appetite suppression decreases within a few weeks. However, this does vary from individual to individual but apparently is inevitable. This may shed some light on how Adipex works at least in part.

Phentermine/Adipex stimulates certain neurons to release a group of neurotransmitters called catecholamines. Catecholamines include dopamine, epinephrine and norepinephrine. These neurotransmitters are known to elicit a “fight or flight” response. When you run away from something (flight) or need to confront someone (fight), the last thing you want to do is eat something. So, these neurotransmitters inhibit hunger signals making you less interested in food and hence you lose your appetite. This may also be due to Adipex’s affects on leptin levels in the brain as well. It is thought that Adipex can raise levels of leptin which is a hormone that tells the brain that you are full and don’t eat any more. It is also believed that increased levels of catecholamines inhibit another chemical messenger know as neuropeptide Y. Neuropeptide Y is known to initiate eating while decreasing energy usage and increasing the storage of fat. So, the catecholamines are activating several pathways some of which inhibit the brain and others excite.

Now that we have that under our belts, let’s go back to the tolerance problem. Appetite suppressants essentially cause the release of certain neurotransmitters which essentially moves neurotransmitters from one place to another place, however does nothing to help increase the amount of neurotransmitters in the brain. In a way, Adipex and other drugs like it, fool the brain into thinking there are more neurotransmitters around than there actually are. The brain’s response to this is that the brain makes less neurotransmitter than it should. You are actually depleting your own neurotransmitter stores. Not to fear! It is possible to reverse the depletion of neurotransmitters and get ride of tolerance. A group of researchers have developed a solution to this problem known as amino acid therapy. Most neurotransmitters are made with amino acids so an extra supply of amino acids should initiate neurotransmitter production and return the system back to normal.

What to do if you Adipex Tolerance

The online “virtual consultation” prescription was no longer valid.  Now, you have to have a real physical consultation (in your doctor’s office) to get a prescription for Adipex.  However, you can still buy Adipex online with a prescription.  Websites trying to sell Adipex online without a prescription is illegal.  If you order without a real prescription from your doctor,  the product you buy will be a fake product.

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