​Qsymia is a weight loss drug in an extended-release form that is a combination of Phentermine and Topiramate. Phentermine is used to suppress appetite and Topiramate is used primarily to treat epilepsy and prevent migraines. Topiramate has a common side effect of generating weight loss and enhances the effects of Phentermine. Qsymia has no generic alternative available at this time.


  • Dosage forms and strengths:
  • Capsules (Phentermine mg/Topiramate mg extended-release)
  • 3.75 mg/23 mg (starting dose)
  • 7.5 mg/46 mg (recommended dose)
  • 11.25 mg/69 mg (titration)
  • 15 mg/92 mg (highest dose)

Qsymia 3.75 mg/23 mg and 11.25 mg/69 mg are for titration purposes.

Indications and Usage

Qsymia is used in conjunction with a reduced-calorie diet and exercise for chronic weight management in adults who have an initial body mass index (BMI) of:

  • 30 kg/m2 or greater (medically obese), or
  • 27 kg/m2 or greater (overweight) and at least one weight related comorbidity such as diabetes type-2, high cholesterol or hypertension.

General Dosing and Administration

​For those of you who are not familiar with body mass index (BMI), we’ll take a look at it here. BMI is calculated by dividing your weight (in kilograms) by height (in meters) squared. You can use a conversion chart from the internet to use pounds and inches.

If you have an initial BMI of 30 or greater or 27 with comorbidities, your dosage of Qsymia would be:

Start therapy with one capsule of Qsymia (3.75 mg/23 mg) daily for 14 days taken in the morning with or without food. After 14 days increase to the recommended dose of Qsymia 7.5 mg/46 mg once daily.

  • Weight will be evaluated after 12 weeks. If the patient has not lost at least 3 percent of their baseline weight, discontinue or raise the dose. To raise the dose, increase to one capsule 11.25 mg/69 mg for 14 days once daily.
  • After 12 weeks of treatment, evaluate weight loss again.
  • If patient has not lost 5 percent of baseline weight, therapy is discontinued.
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Qsymia Cost

Initially, Vivus (manufacturer of Qsymia) didn’t expect private or public insurances to pay for Qsymia prescriptions so you will probably have to pay out of pocket. According to WebMD, the wholesale price of Qsymia for a 30 day supply is: (Phentermine mg/Topiramate mg)

  • Low dose (starting dose) – 3.75 mg/23 mg – $120.00
  • Recommended doses – 7.5 mg/46 mg – $135.62
  • Three-quarter dose – 11.25mg/69 mg – $162.74
  • Top dose – 15 mg/92 mg – $183.90

The above prices are what the pharmacies pay, not you.  Online, 30 day supply may cost as much as following:

  • Low dose (starting dose) – 3.75 mg/23 mg – $185 to $245
  • Recommended doses – 7.5 mg/46 mg – $193 to $257
  • Three-quarter dose – 11.25mg/69 mg – $207 to $266
  • Top dose – 15 mg/92 mg – $206 to $266

Currently, Qsymia is available at Kroger, Target (CVS), Walgreens, Safeway, Walmart, Sams Club, Rite-Aid, CVS pharmacies, Publix and Kmart. There are coupons and discounts available for Qsymia. Check out PhenObestin – Qsymia alternative without prescription. Some other sites offer a start Qsymia for free program and you can continue to save for 36 months. These sites usually say you’ll get the first 14 days free (3.75 mg/ 23 mg) starter dose or you can opt for saving up to $95 on your first 30 day prescription at any dose. From there you can save up to $65 per month for 36 months. This monthly saving offer requires an activated Program ID prior to use. You must have a valid prescription. Also, search for Qsymia coupons on the internet.

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  • Web MD - Phentermine Oral : Uses, Side Effects, Interactions, Pictures, Warnings and Dosing - WebMD.
  • Drugs.com - Phentermine: Drug Uses, Dosage and Side Effects - Drugs.com.
  • Mayoclinic.org - Phentermine for weight loss - Mayo Clinic.
  • MedinePlus.gov- Phentermine: MedlinePlus Drug Information
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5 stars - "I lost over 50 pounds on Phentermine. It definitely works. Took me 12 months." Based on 110,123 Votes since 2013!
  • MedicineNet.com - Phentermine Weight Loss Drug Side Effects, Dosage, Safety & Alcohol Effects.
  • RXList.com - Phentermine (phentermine hydrochloride): Side Effects, Dosages, Treatment, Interactions, Warnings
  • EverydayHealth.com - Phentermine Reviews - Everyday Health
  • HealthLine.com - Phentermine - Side Effects, Dosage, Uses, and More.

(Last Updated On: 29th May 2022)